Hiroaki Yokota

Hiroaki Yokota
Associate Professor / Doctor of Science (Osaka University)

Fields of specialization

  • Biophysics
  • Physiology
  • Life sciences

Supported topics

  • Collaborative research
  • Technical consultations (optical microscopy, low-light detection, nanobiology)
  • Online lectures (advanced fluorescence microscopy, biophysics-related topics such as single-molecule measurement of biomolecules)

Message

I would like to support business development based on my knowledge and expertise in life sciences.

Research themes

Optical visualization and measurement of life phenomena
  • Direct visualization of single protein molecules
  • Single-molecule DNA manipulation
  • Development of fluorescence microscopy for disease diagnosis and drug discovery

Social contribution activities

  • Promotion of Biophotonics Design
  • A-SAP (Access Center for Innovation Solutions, Actions and Professionals) Industry-Academia-Government-Finance
  • Collaboration Innovation Promotion Project
  • ikollabo Hamamatsu (Hamamatsu Medical Engineering Collaboration Center)

It’s NEW 

  • Yokota, H. DNA-unwinding dynamics of Escherichia coli UvrD lacking the C-terminal 40 amino acids. Biophys. J. 118, 1634-1648 (2020).
  • Yokota, H. Roles of the C-terminal amino acids of non-hexameric helicases: Insights from Escherichia coli UvrD. Int. J. Mol. Sci. 22, 1018 (2021).
  • Yokota, H. DNA unwinding and oligomerization dynamics of Escherichia coli UvrD helicase revealed by single-molecule fluorescence imaging. SEIBUTSU-BUTSURI 61, 277-231 (2021).
  • Yokota, H. Quantitative and kinetic single-molecule analysis of DNA unwinding by Escherichia coli UvrD helicase. Biophys. Physicobiol. 19, e190006 (2022).
  • Yokota, H. Fluorescence microscopy for visualizing single-molecule protein dynamics. Biochim. Biophys. Acta Gen. Subj. 1864, 129362 (2020).
  • Yokota, H., Fukasawa, A., Hirano, M., Ide, T. Low-light photodetectors for fluorescence microscopy. Appl. Sci. 11, 2773 (2021).

Research keywords

  • Single-molecule fluorescence imaging
  • Single-molecule DNA manipulation
  • Protein-DNA interactions
  • Optical microscopy
  • Fluorescence microscopy
  • Nanobiology
  • Fluorescent probes
  • Microfabrication
  • Low-light photodetectors
  • Spectrophotometers
  • Fluorescence spectrophotometers
  • Biochemistry
  • Genetic engineering

1955-1, Kurematsu-cho, chuo-ku, Hamamatsu, Shizuoka, 431-1202, JAPAN
TEL : 053-484-2501 FAX : 053-487-3012

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